Evidence-based wound care

Clinical Evidence and Case Studies

Successful wound management needs a commitment to evidence-based care.

Evidence-based wound care empowers clinicians to make informed decisions that enhance healing, minimize complications, and improve patient experiences. This approach ensures that every product, treatment, and care plan is backed by data, helping clinicians deliver consistent, high-quality care with confidence.

Research library

Explore the Evidence

Review clinical studies, case series, and real-world evidence across the Hydrofera Blue® portfolio.

Cover preview for Improving the Quality of Chronic Wound Care Using an Advanced Wound Management Program and Gentian Violet/Methylene Blue-Impregnated Antibacterial (GV/MB) Dressings: A Retrospective Study

Improving the Quality of Chronic Wound Care Using an Advanced Wound Management Program and Gentian Violet/Methylene Blue-Impregnated Antibacterial (GV/MB) Dressings: A Retrospective Study

Author: Theresa Hurd, PhD, MScN, MSN, ACNP, RN
Products Covered: Hydrofera Blue CLASSIC® Hydrofera Blue READY®

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Cover preview for Gentian Violet and Methylene Blue Polyvinyl Alcohol Foam Antibacterial Dressing as a Viable Form of Autolytic Debridement in the Wound Bed

Gentian Violet and Methylene Blue Polyvinyl Alcohol Foam Antibacterial Dressing as a Viable Form of Autolytic Debridement in the Wound Bed

Authors: Andrew Joseph Applewhite, MD Brock Liden, DPM Paul Attar, PHD, MBA Quyen Stevenson, ARNP, CWOCN
Products Covered: Hydrofera Blue CLASSIC®

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A Prospective Study to Evaluate Methylene Blue and Gentian Violet Dressing for the Management of Chronic Wounds

Authors: Kevin Y. Woo, PhD, RN, FAPWCA Jolene Heil, RN, ET, MCIScWH
Products Covered: Hydrofera Blue CLASSIC®

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The Use of Gentian Violet and Methylene Blue Impregnated Foam for Treatment of Chronic Leg Ulcers

Authors: Alexander Savage Lisa J. Ellis Patricia Terrill
Products Covered: Hydrofera Blue CLASSIC®

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Pyoderma Gangrenosum Treatment: A Steroid Free Option

Authors: Patricia Conwell R.N., B.S., C.W.C.N. Lisa Mikulski R.N., B.S.N. Debra Moran R.N. Mark Tramontozzi M.D., F.A.C.S.
Products Covered: Hydrofera Blue CLASSIC®

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Cover preview for Use of a Collagen Dressing in Conjunction with Gentian Violet/Methylene Blue Pre-Moistened Wide-Cell Polyvinyl Alcohol Antibacterial Foam in the Treatment of Wounds with Necrotizing Fasciitis – Case Series

Use of a Collagen Dressing in Conjunction with Gentian Violet/Methylene Blue Pre-Moistened Wide-Cell Polyvinyl Alcohol Antibacterial Foam in the Treatment of Wounds with Necrotizing Fasciitis – Case Series

Author: Maria Aguinaga MD FAPWCA
Products Covered: Hydrofera Blue COMFORTCEL®

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Cover preview for Innovative Use of Gentian Violet/Methylene Blue (GV/MB) Impregnated Polyvinyl Alcohol (PVA) and Polyurethane (PU) Foams in a Complex Wound Care Case

Innovative Use of Gentian Violet/Methylene Blue (GV/MB) Impregnated Polyvinyl Alcohol (PVA) and Polyurethane (PU) Foams in a Complex Wound Care Case

Author: Linda Concepcion, BSN, RN, WCC
Products Covered: Hydrofera Blue CLASSIC® Hydrofera Blue READY®

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Use of an Antibacterial Foam Ostomy Dressing for the Management of Peristomal Skin Problems

Authors: Neal Dunwoody, BSN, RN, BA, CWON Tami Walker, BSN, RN, CWOCN Jane Theriault, BSN, RN, CWOCN
Products Covered: Hydrofera Blue CLASSIC® Ostomy

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Neonatal Abdominal Incision Dehiscence and Treatment

Authors: Tess Aberg, MSN, FNP-BC, CWON Sarah Wilhite, BSN, RN, CWON Dr. Simone Hyman
Products Covered: Hydrofera Blue CLASSIC®

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Cover preview for Gentian Violet/Methylene Blue Polyurethane Foam in the Longitudinal Management of a Large Abdominal Wound in a Preterm Neonate

Gentian Violet/Methylene Blue Polyurethane Foam in the Longitudinal Management of a Large Abdominal Wound in a Preterm Neonate

Authors: Lisanne Pessini, Wound and Ostomy APRN, BSN, RN, MSN, CPNP-PC/AC Matthew Tolliver, BSN, RN, C-WOCN
Products Covered: Hydrofera Blue READY®

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Successful Management of Complex Pediatric and Neonatal Wounds with Methylene Blue and Gentian Violet Foam Dressings

Author: Vita Boyar, MD
Products Covered: Hydrofera Blue CLASSIC®

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Cover preview for Case Series of Lower-Extremity Chronic Wounds Managed with an Antibacterial Foam Dressing Bound with Gentian Violet and Methylene Blue

Case Series of Lower-Extremity Chronic Wounds Managed with an Antibacterial Foam Dressing Bound with Gentian Violet and Methylene Blue

Authors: Patricia M. Coutts, RN, IIWCC Judy Ryan, RN, IIWCC R. Gary Sibbald, BSc, MD, MEd, FRCPC(Med Derm), MACP, FAAD, MAPWCA
Products Covered: PVA Foams

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